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About Welchol

Welchol, along with diet and exercise, is the only FDA-approved medicine with a single active ingredient proven to lower both high blood sugar (A1C) and LDL-C or “bad” cholesterol in adults with type 2 diabetes and high cholesterol.


Photos depict models, not actual patients or healthcare professionals.

Benefits of Welchol

2 benefits of Welchol
Welchol® Lowering LDL-C and A1C Welchol® Lowering LDL-C and A1C

Welchol is not for everyone, especially those with:

  • a history of intestinal blockage,
  • blood triglyceride levels of greater than 500 mg/dL, or
  • a history of pancreatitis (inflammation of the pancreas) due to high triglyceride levels

Welchol for lowering high blood sugar

Welchol for lowering high blood sugar (A1C)

In general, for adults with type 2 diabetes, the American Diabetes Association suggests an A1C level of 7%1,2

Work with your doctor to find out the right A1C level for you.

For people with type 2 diabetes, your A1C is an important number. If your blood sugar is almost 7%, that isn't a bad place to be. After all, any improvement in blood sugar—no matter how small—is important. Welchol could help you go further. In 3 pivotal studies, Welchol, when added to metformin, sulfonylurea, or insulin therapy, helped lower A1C by 0.5%, as compared to placebo—a significant reduction.

In clinical trials, the adverse reactions observed in ≥2% of patients, and more commonly with Welchol than placebo (“sugar pill”), regardless of investigator assessment of causality seen in:

  • Adult patients with Type 2 Diabetes were:
    constipation, low blood sugar (hypoglycemia), indigestion (dyspepsia), nausea, high blood pressure (hypertension), and back pain

Welchol may increase blood levels of metformin when taking metformin extended release (ER).

Check with your doctor about monitoring your blood sugar levels.

Welchol has not been studied with all anti-diabetes medications.

Please see Important Safety Information about Welchol below.

Welchol for bad cholesterol

Welchol for “bad” cholesterol

Continue your journey toward lowering LDL-C or “bad” cholesterol levels with Welchol

Welchol—when added to diet, exercise, and a cholesterol-lowering medicine called a statin—may help you keep moving forward. Have a look at these results from clinical studies:

  • In two different studies, when added to either 10 mg of simvastatin or atorvastatin, combination therapy with Welchol lowered "bad" cholesterol by 42% and 48%, respectively*

 

In clinical trials, the adverse reactions observed in ≥2% of patients, and more commonly with Welchol than placebo (“sugar pill”), regardless of investigator assessment of causality seen in:

  • Adult patients with high LDL ("bad") cholesterol were:
    constipation, indigestion, nausea, accidental injury, weakness, sore throat, flu-like symptoms, runny nose, and muscle aches
  • Pediatric patients with high LDL ("bad") cholesterol were:
    inflamed nasal passages and throat, headache, fatigue, creatine phosphokinase (a muscle enzyme) increase, runny nose, and vomiting

Welchol is not for everyone, especially those with intestinal blockage, those with blood triglyceride levels of greater than 500 mg/dL, or those with a history of pancreatitis (inflammation of the pancreas) due to high triglyceride levels.

It is recommended that your healthcare professional check your lipid levels (including your triglycerides [TG] and non–high-density lipoprotein cholesterol [non–HDL-C]) before starting Welchol and periodically thereafter.

*Patients did not have to have type 2 diabetes to be in these 2 studies.

Please see Important Safety Information about Welchol below.

Take the Next Step

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Take the Next Step and Save!

Sign up to be a member of the ADDvantage ProgramTM and learn more about the Welchol Savings Card.

START SAVING

Not all patients are eligible, see program terms and conditions.

Savings for Welchol are subject to a maximum benefit of $70 for a 30-day prescription and $125 for a 90-day prescription. Other restrictions apply.

*Based on a $24 co-pay for a 90-day supply
†Based on a $25 co-pay for a 30-day supply

Important Safery Information

What is Welchol® (colesevelam HCI)?

Welchol, along with diet and exercise, lowers LDL or “bad” cholesterol. It can be taken alone or with other cholesterol-lowering medications known as statins.

Welchol lowers LDL cholesterol in boys, and in girls who have had a menstrual period, ages 10 to 17 years, with a condition known as heterozygous familial hypercholesterolemia (a genetic disorder that causes high cholesterol) alone or with other cholesterol-lowering medications known as statins after inadequate control with diet alone.

Welchol, along with diet and exercise, also lowers blood sugar levels in adult patients with type 2 diabetes mellitus when added to other anti-diabetes medications (metformin, sulfonylureas, or insulin).

Welchol should not be used to treat type 1 diabetes or diabetic ketoacidosis.

Welchol has not been studied with all anti-diabetes medications.

Welchol has not been studied in children younger than 10 years old or in girls who have not had a menstrual period.

Important Safety Information About Welchol (colesevelam HCI)

Welchol is available by prescription only. Ask your HCP if Welchol is right for you.

Welchol is not for everyone, especially those with:

  • a history of intestinal blockage,
  • blood triglyceride levels of greater than 500 mg/dL, or
  • a history of pancreatitis (inflammation of the pancreas) due to high triglyceride levels.

Welchol has not been shown to prevent heart disease or heart attacks.

Tell your health care provider (HCP) if you have high triglycerides (greater than 300 mg/dL).

Tell your HCP if you have stomach or intestinal problems, including gastroparesis (when the stomach takes too long to empty its contents), abnormal contractions of the digestive system, a history of major gastrointestinal tract surgery, if you have trouble swallowing, or if you have vitamin A, D, E, or K deficiencies.

Welchol has known interactions with cyclosporine, glimepiride, glipizide, glyburide, levothyroxine, certain birth control pills, olmesartan medoxomil, and metformin extended release (ER). Welchol has not been studied with all combinations of drugs and supplements. Please tell your HCP about all medications and supplements you may be taking before beginning Welchol, as your HCP may tell you to take your other medications and supplements 4 hours before taking Welchol.

Remember to tell your HCP if you are pregnant, plan to become pregnant, or are breastfeeding.

Welchol (colesevelam HCl) for Oral Suspension should not be taken in its dry form.

Welchol for Oral Suspension is recommended for, but not limited to, use in appropriate pediatric patients as well as any patient who has difficulty swallowing.

Phenylketonurics: Welchol for Oral Suspension contains 27 mg phenylalanine per 3.75 gram dose.

In clinical trials, the adverse reactions observed in ≥2% of patients, and more commonly with Welchol than placebo (“sugar pill”), regardless of investigator assessment of causality seen in:

  • Adult patients with high LDL (“bad”) cholesterol were:
    constipation, indigestion, nausea, accidental injury, weakness, sore throat, flu-like symptoms, runny nose, and muscle aches
  • Pediatric patients with high LDL (“bad”) cholesterol were:
    inflamed nasal passages and throat, headache, fatigue, creatine phosphokinase (a muscle enzyme) increase, runny nose, and vomiting
  • Adult patients with Type 2 Diabetes were:
    constipation, low blood sugar (hypoglycemia), indigestion (dyspepsia), nausea, high blood pressure (hypertension), and back pain

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

For patients having difficulty affording their Daiichi Sankyo medication, please call the Daiichi Sankyo Patient Assistance Program at 1-866-268-7327 for more information or visit www.dsi.com/news/patientassistance.html.

Click here for full Product Information about Welchol.

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